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ACL injury - assessment and conservative care
ACL evaluation, trial evidence for non-operative care, complications and prevention.
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48 questions
Q1What is the X-ray finding of an ACL tear?▸
Segond fracture on X-ray = ALL avulsion
Associated with ACL tear 75-100% of the time
Q2What are the sagittal MRI findings of an ACL tear?▸
Discontinuity/waviness of fibres on T2
Abnormal orientation (too flat compared with Blumensaat's line)
PCL buckled
Anterior translation of the tibia
Q3What are the coronal MRI findings of an ACL tear?▸
Discontinuity of fibres
Bone bruise in the LFC (middle 1/3) and lateral tibial plateau (posterior 1/3)
Effusion
Q4What is the axial MRI finding of an ACL tear?▸
Fluid at the intercondylar notch = empty notch sign
Q5What are the physical examination findings of ACL deficiency?▸
Palpate the bony prominence; feel step off bilaterally
Pivot shift (page, jerk, clunk)
IR + valgus anterolaterally subluxes the tibia
Flexing the knee changes the ITB from extensor to flexor and reduces the tibia
Q6Why examine the collateral ligaments at 30 degrees of flexion?▸
At 30 degrees of flexion the capsule and cruciate ligaments relax
This allows isolated assessment of the collateral ligaments
Q7What injuries are associated with an acute ACL tear?▸
Lateral meniscal tear in 54% of acute ACL injuries
Unhappy triad = ACL + MCL + medial meniscus
Q8What is the anatomy and function of the anterolateral ligament (ALL)?▸
Origin: anterior and distal to the femoral attachment of the LCL
Insertion: Gerdy tubercle on the tibia
Contributes to tibial internal rotation stability
Failure causes rotational instability; treated by ALL reconstruction or LET
Q9What is the biomechanical difference between ALL reconstruction and LET?▸
ALL - non-isometric (tight in extension, slack in flexion), allowing physiological internal rotation at 90 degrees flexion
LET (modified Lemaire) - isometric, with a tendency to limit physiological internal rotation at 90 degrees flexion
Q10What are the results and downsides of the STABILITY trial (AJSM 2020)?▸
Adding LET to single bundle ACLR in young high-risk patients results in a statistically significant, clinically relevant reduction in graft rupture and persistent rotatory laxity at 2 years
Downside: more pain and worse outcome scores in the first 3-6 months
Slower return to sport
Long-term studies suggest increased risk of lateral compartment OA
Q11What are the indications for ALL reconstruction or LET?▸
2 of 3: Grade 2 pivot shift or greater
Desire to return to high-risk/pivoting sport
Generalised ligamentous laxity
Q12What is the location of the ACL?▸
Intra-articular, extrasynovial - no haematoma formation; synovial fluid has a surfactant effect
From the medial surface of the LFC (bifurcate ridge) to the anterior tibia, just anterior and between the intercondylar eminences
Q13What are the dimensions and composition of the ACL?▸
~33mm length, 11mm width
90% type 1 collagen, other type 3
Q14What are the anteromedial and posterolateral bundles of the ACL?▸
AM bundle: more isometric, tight with the knee in flexion, controls AP translation more
PL bundle: tight in extension, controls rotation more
Q15What is the blood and nerve supply of the ACL?▸
Blood supply: middle geniculate artery
Nerve supply: posterior articular branch of the tibial nerve
Q16What is the function of the ACL?▸
Provides 85% of the stability preventing anterior translation of the tibia
Secondary restraint to valgus and varus stress and tibial rotation
2200N load to failure
Q17What is the mechanism of an ACL injury and what causes locking?▸
Non-contact pivoting injury
Valgus + external rotation, partially flexed
Landing with the knee in extension
Cause of locking in an ACL tear: the stump
Q18What is the natural history of the ACL-deficient knee (Frank Noyes JBJS 1983)?▸
1/3 have no/minimal symptoms in ADL or recreational activity
60% had repeated injury and meniscal/cartilage injury within 2 years
1/3 give up sport
1/3 deteriorate and require surgical stabilisation
Q19When should ACL reconstruction be performed?▸
Delay around 6/52
Allow effusion and inflammation to subside
Regain good ROM and good quadriceps control
To avoid arthrofibrosis
Q20What factors determine whether to perform ACL reconstruction?▸
Return to sports, especially pivot type
Prevent second injury - cartilage and meniscus
Theoretically reduces DJD, yet no concrete evidence (ACL deficiency puts more stress on the posterior horn of the medial meniscus)
Q21What are the graft options and their loads to failure?▸
BPTB - 2600N, size 10mm
Hamstring - 4000N, size 7-8mm
Quadriceps tendon - 2500N, mainly for revision cases
Return to sport/repeat injury and ROM/failure rate are the same for BPTB and hamstring
Q22What are the pros and cons of a BPTB graft?▸
Pros: early healing (animal study), bone-to-bone -> faster rehab
Cons: patella fracture (stellate) or PT rupture 0.5%, graft-tunnel mismatch
Anterior knee pain (15%)/PFJ OA - cannot kneel; patellar baja from retropatellar fibrosis; some flexion contracture
Q23What are the pros and cons of a hamstring graft?▸
Pros: high tensile strength, easier/smoother passage
Cons: not used in generalised ligamentous laxity or complete MCL injury - do not jeopardise medial stability
Q24What are the problems with allograft and artificial grafts?▸
Allograft: fresh frozen risks infection; irradiation weakens the graft; quality not as good, not enough supply
Artificial: no incorporation, a lot of synovitis and pain, cannot absorb energy (stress-strain curve has no toe phase and is steep)
Q25What are the advantages of autograft versus allograft?▸
Autograft: less immunogenicity, less disease transmission, faster incorporation, lower cost
Allograft: saves harvesting time, bigger graft for revision, no donor site morbidity
Grassi BJJ 2017: autograft has lower rates of postoperative laxity and fewer reoperations/complications; when irradiated grafts are excluded, outcomes are similar
Q26What do KT-1000 measurements show after ACL reconstruction?▸
<3mm compared with the normal side is considered stable, and BPTB is more stable
If the difference is <5mm, BPTB and hamstring show no difference
Ligament has more elastin, is more viscoelastic and elongates less compared with hamstring
Q27Should single or double bundle ACL reconstruction be used?▸
Meta-analysis: double bundle is better for rotational stability but clinical outcome is similar
Prerequisite: footprint at least 11mm
Freddie Fu CORR 2020: <14mm single, 14-18 controversial, >18 double
Q28What are the ideal properties of graft fixation?▸
Strong enough to avoid failure
Stiff enough to restore load-displacement response
Secure enough to resist slippage under cyclic loading
Q29What are the types of suspensory and aperture fixation and their pros and cons?▸
Suspensory: cortical (endobutton, staples, tie over post) or cancellous (transfix, rigidfix)
Pros: more healing surface, more rigid (fixed at closed loop), adjustable length
Aperture fixation: interference screw (depends on friction, longer = more pull-out strength)
Pros: fixation near the articular surface, less bungee effect; Cons: advancement of bone graft, graft/suture laceration, divergent -> less stability
Q30Which fixation is used in the femur, tibia and revision cases?▸
Femoral: usually suspensory +/- double fixation
Tibial: usually aperture +/- double fixation
Revision: poorer bone quality -> double fixation
Reverse thread in the femoral tunnel of the right knee: the graft moves anteriorly and causes laxity (the isometric point is more posterior)
Q31What are the key steps of ACL reconstruction?▸
Low morbidity harvest of a biologically active graft
Short arthroscopy time and prevent intra-articular injury
Accurate identification of the tibial and femoral footprints
Smooth passage of the graft through the tunnels
Robust fixation and tensioning of the graft
Appropriate rehabilitation
Q32Describe the operative details of ACL reconstruction.▸
GA/SA with tourniquet; graft harvesting and preparation (preconditioning reduces stress relaxation)
Femoral tunnel: anatomical footprint, as posterior as possible but prevent blow out, coronally at 9-10 o'clock if done on the right knee
Tibial tunnel: anatomical footprint (centre 10-11mm in front of the anterior border of the PCL), trajectory <75 degrees from horizontal (55 degrees guide used)
Intraoperative: tunnel malposition, graft fixation problems (interference screw laceration/divergence, endobutton blow out at lateral cortex), poor tensioning, injury to secondary stabilisers
Postoperative: notch impingement (cyclops lesion around the tibial tunnel), stiffness/arthrofibrosis, infection, late patella fracture/anterior knee pain/patella tendon rupture (BPTB graft)
Q34Describe the phases of graft ligamentisation and healing.▸
Early healing 0-6 months: inflammatory cytokines (IL6, TNF alpha, TGF beta, metalloproteinase 1 and 13) digest collagen; graft undergoes central avascular necrosis; maximum increase in anterior laxity at 6 months
Proliferation 6-12 months: Revascularization from the synovium, infrapatellar fat pad and pseudoligamentum mucosum, increased expression of the VEGF; Repopulation by progenitor cells from the autograft, bone tunnel and seeding fibroblasts from the residual stump lay down type III collagen
Maturation/ligamentisation >12 months: osseous integration by enchondral ossification; collagen remodelled to type I collagen
Q35What are the 4 zones of tendon-to-bone healing?▸
Fibrous tissue surrounds the graft
Collagen grows into the fibrous tissue
Fibrocartilaginous tissue forms and then becomes bone
This is fibrocartilaginous healing
Q36What are the phases of ACL rehabilitation?▸
Phase 1 (postop 1 week) [ROM + ADL]: cryotherapy for swelling and pain, obtain ROM 0-90 especially full extension, immediate weight bearing
Phase 2 (postop 2-8 weeks) [strengthening]: full ROM, isometric and isotonic exercise, commence close and open chain exercise
Phase 3 (postop 8-16 weeks) [functional]: isokinetic and endurance, increase resistance of OC/CC exercise from 9 weeks, plyometric exercise, normal running from 13 weeks
Phase 4 (postop 16-22 weeks) [sport specific + injury prevention]: Neuromuscle ex optimization, jumping, agility; return to sport when HQ ratio >0.8
Q37What are the principles of ACL rehabilitation?▸
The cornerstone is ROM, strengthening, functional exercise and injury prevention, facilitating ligamentisation and graft healing
Avoid excessive stress on the graft: initial closed chain (open chain: distal limb unsupported -> increases shear force by gravity)
Eccentric quadriceps strengthening; isometric hamstring and quadriceps exercise
Avoid isokinetic quadriceps or open chain exercise in the early post-op period
Q38How is a dropped graft managed intra-operatively?▸
Retrieve from the floor within 15 seconds
Remove all sutures; soak in saline
Soak in 2% chlorhexidine
Soak in triple antibiotics (gentamicin, clindamycin, polymyxin)
Minimise sutures in the graft, consider monofilament sutures; longer antibiotics and more frequent follow-up
Q39What are the pros and cons of one-stage versus staged meniscus and ACL surgery?▸
One stage pros: one GA
Biological: drilling of tunnels provides MSC for meniscus healing
Mechanical: restores a stable environment for meniscus healing
Cons: contradictory rehab -> arthrofibrosis; for a locked knee go 2 stage (meniscus then early ACLR)
Q40What was the design of the study of operative versus conservative management?📷▸
100 patients randomly assign OT/ conservative Mx
100 patients randomly assigned to operative (ACL reconstruction) or conservative management
Q41What were the key findings of the study?▸
ACL reconstruction per se did not reduce risk of OA or improve outcome scores
ACL reconstruction can reduce risk of 2nd meniscal injury
Meniscal status is the most important predictor of OA
Q42What happened to the conservatively managed patients?▸
1/3 of conservative patients later received ACL reconstruction due to instability
Q43What are the intraoperative complications of ACL reconstruction related to graft harvest?▸
Hamstring: premature harvest, deep MCL injury, hematoma, saphenous nerve injury
BPTB: fracture (patella or tibia)
Both grafts: dropped graft
Q44What complications can occur during tunnel placement in ACL reconstruction?▸
MFC injury
Lateral wall blowout
Posterior wall blowout
Q45What complications can occur during graft passage in ACL reconstruction?▸
Under-sized graft
Over-sized graft
Q46What complications can occur during graft fixation in ACL reconstruction?▸
Late button flip
Screw breakage or slippage
Screw divergence
Graft laceration, advancement or rotation
Screw protrusion into the joint
Q47What postoperative complications are related to ACL reconstruction?▸
Cyclops lesion
Arthrofibrosis
Septic arthritis
Prominent tibial screw
Q48How are postoperative complications of ACL reconstruction classified?▸
Related to ACLR: cyclops, arthrofibrosis, septic arthritis, prominent tibial screw
Not related to ACLR (listed as a separate category by the lecturer; no examples given in the notes)