Q9How useful is hip aspiration and how is it performed?▸
Spangehl: sensitivity 0.86, specificity 0.94, PPV 0.67, NPV 0.98 (level 1); suggest in high clinical suspicion with abnormal ESR/CRP
Anterior approach: 1 inch lateral to femoral pulse, 1 inch below inguinal ligament; lateral approach at GT under XR guidance; US or XR guided
Off antibiotics for at least 1 week; no intra-articular LA (bacteriostatic)
Send immediately for GS/C+ST, PCR and total cell count (>3000 cells/ml, >80% polymorph); different instruments from 3 different sites, 2/3 samples positive
Q10What are the MSIS criteria and common pathogens for PJI?▸
Staph aureus and Staph epidermidis account for 2/3; also E. coli, enterococcus
Q11What are the principles of management of a chronic infected THR?▸
MDT approach with MSK radiologist, microbiologist, histopathologist, plastic surgeon and experienced revision arthroplasty surgeon
2-stage revision: removal of implant, debridement and antibiotic-loaded cement spacer
Systemic antibiotics 6-12 weeks with monitoring; repeat hip aspiration at 6 weeks; CT to reassess bone stock
Second stage if infection free and serology negative x 2 weeks; must use cemented components (no ingrowth); frozen section negative if <5 polymorphs per 400x HPF
One stage only if host not immunocompromised, low-virulence organism, no sinus tract, no OM/loosening
6 vs 12 weeks antibiotics non-inferior (NEJM 2021 Bernard RCT)
Q12How does the timing of infection determine management?▸
<4 weeks: acute infection with less biofilm - radical debridement, exchange of modular bearing (thorough debridement), IV antibiotics
Q13How do the KLIC and CRIME 80 scores guide DAIR?▸
KLIC for Tsukayama type 2 early acute: kidney 2, liver 1.5, indication (fracture/revision) 1.5, cemented 2, CRP>115 2.5; score >4 = 55% failure rate
CRIME 80 for type 3 acute haematogenous: COPD 2, CRP>150 1, RA 3, indication fracture 3, male 1, exchange mobile component -1, age >80 2; score >3 = 60% failure
Q14What is the antibiotic-loaded cement recipe used for spacers?▸
Options are gentamicin, vancomycin, tobramycin
1 pack cement (40g) with 1 bottle antibiotic (4g vancomycin); ~10% (~1.x g gentamicin)
No vacuum, no drain; local concentration falls to 1/2 after 10 days
Q15What are the reported success rates of one-stage and two-stage revision?▸
UCLH experience: TKR 1 stage 100%, 2 stage 93.2%
THR 1 stage 94.5%, 2 stage 91.8%
Ongoing ccc
Q16What history and examination findings are important in a painful THR?▸
History: age and premorbid state, nature of pain, infection symptoms, current function (HHS), details of last operation, rule out spine, neuro, PVD as causes of pain
PE: scar, deformity, sinus, ROM
ROM clues: stiff - HO/impingement/contracture; end range pain - impingement; all range pain - infection; IR/ER pain - femoral stem loose
Stinchfield test (resisted flexion ~SLR) suggests acetabular loosening; assess abductors
Q17What investigations are needed?▸
CT
Scannogram + scoli series
Q18What are the aims of revision THR?▸
Restore offset and LLD
Replenish bone stock
Secure and accurate placement of components
Q19What pre-operative preparation is required?▸
Counsel patient regarding prognosis of revision THR; check previous implant and approach
Prepare instruments for implant removal: AO large fragment, ex-plant, straight/curved osteotome, high speed burrs, cement splitters, US device, flexible light source, allograft, GTR plate and cables if planning ETO
Inform pathology lab for intraop frozen section; prepare cement spacer in case frozen section is positive
Q20What are the key intra-operative steps for femoral implant removal?▸
Intraop 1g tranexamic acid to reduce blood loss; old incision, protect sciatic nerve
Remove bone/cement at Gruen zone 1; try hammering implant out with anchorage at collar/head/hole
Remove cement mantle with osteotome, reamer, burr, K wires, cement splitter (split radially then longitudinally)
+/- trochanteric osteotomy/trochanteric page/ETO; if cement mantle is good, use tap in and tap out (cement on cement)
Q21What are the principles of an extended trochanteric osteotomy (ETO)?▸
Preserve abductor and vastus lateralis (blood supply to the flap); divide the lateralis insertion off the vastus tubercle and elevate vastus lateralis off the linea aspera
Less than 1/3 of the femoral circumference; length determined by the length of the cement mantle
Multiple drill holes then break with osteotome; fix with cables
Q22What is a bone window and why may implant removal be difficult?▸
Bone window by burr - create a trough over the posterior femur, remove the fenestrated part and dissect the bone block
Difficulty in removal of an AMA is due to bone growth into the fenestration
Q23How is a broken femoral stem removed?▸
From above: trephine reamer
From below: cortical window
From the side: ETO
Q24What ultrasonic and other methods are used to extract cement?▸
Fish-bone like ultrasonic tip - melts the cement, sinks into it, hardens when USG is off, then hammered out
Dish-like tip - just melts and lets cement leak through holes
Drill and tap; segmental cement extraction (long screw with multiple nuts, pour in new cement, hammer out each nut sequentially - cement is weak in tension)
Powered cement reamer - easy fracture especially over the lateral or anterior side
Q25How is the acetabular implant removed, including a ceramic liner?▸
Curved osteotome
Explant
Ceramic liner: disengage the smooth taperlock by a sharp tap into the liner, then use a suction cup with scallops that contact the peripheral rim of the metal shell to remove the liner
Q26How is reconstruction planned for the femur and acetabulum?▸
Prefer cementless components if previous cement was used - bone surface become sclerotic, making cement interdigitation difficult
Femur: long cementless stem with diaphyseal fixation and adequate distal scratch fit
Acetabulum: identify anatomy with landmarks, navigation, intraoperative imaging, robot
Rim defect: metal augment, strut graft; medial wall defect: morcelised bone graft, anti-protrusion cage
Pelvic discontinuity: cup cage construct; rim stable: line-to-line fit with screw fixation; standby dual mobility cup
Ideally 36mm head
Q27What are the principles and complications of femoral impaction bone grafting?▸
Retrograde canal filling with impacted particulate graft
Segmental defect -> contained defect -> allows subsidence + cement creep -> even load distribution -> bone remodelling
Technique: mesh + wiring creates a neomedullary canal for a cemented femoral stem; advantage: preserves bone stock
Q30If infection is excluded, what causes aseptic loosening and what is your pre-operative assessment?▸
Mild eccentric wear suggesting osteolysis
Request initial post-op X-ray: poor cementation technique (<2mm cement mantle) and poor implant positioning (varus stem, increased cup open angle) cause abnormal stress
Bloods for inflammatory markers and previous X-ray for comparison
Pre-op CT for bone stock, column and rim integrity; CT angiogram for proximity of great vessels to the cup
Trace old records for implant size, brand and removal instruments
If fit for OT, offer operation irrespective of symptoms to prevent further bone stock loss
Q31What are the goals, principles and key surgical considerations of revision hip surgery?▸
Goal: painless, stable, mobile hip free of infection
Principles: stable cup fixation with 70% host bone contact, replenish bone stock, restore hip centre, LLD and offset
Use previous approach, dissect from virgin plane, protect sciatic nerve and gluteus medius
Frozen section: >5 neutrophils/HPF means treat as infection
Long stem with extended coating for distal fixation; prepare allograft/ trabecular metal/ jumbo cup/ ring; accept high hip centre in the elderly
Prepare dual mobility cup and C/XLPE or M/XLPE articulation; slow post-op rehab due to higher dislocation rate
Q32How do you manage acetabular bone defects in revision surgery?▸
Cementless cup prerequisite: 70% cup coverage, 2/3 rim fit, intact columns
Paprosky: 1 minimal lysis; 2 <3cm superior migration; 3 >3cm superior migration with column not intact
Contained defect: avoid defect (high hip centre/ medialise), bone (autograft/allograft, morselized or structural, IBG), metal (wedge, jumbo/oblong cup, cage/ring), cement
Uncontained defect: convert to contained with mesh, then treat as contained with bone graft +/- augment ring
Impaction bone grafting: close segmental defects with flexible metal wire mesh, impact 8-10mm morselized trabecular graft, then cemented cup
Cages offload the graft by bridging ilium or ischium and a liner is cemented in; anti-protrusio cage for pelvic discontinuity
Jumbo cup >62mm women, >66mm men: simple with more host bone contact, but does not restore bone stock, may raise hip centre and has 10% dislocation rate
Q33What are the reasons for a broken cement mantle and how is an extended trochanteric osteotomy (ETO) performed?▸
Cement failure when stresses exceed the fatigue endurance limit of the stem-cement interface and the cement itself
Mantle must be homogeneous and even (2-5mm) with proximal medial cancellous bone <2mm
Stem must be smooth-contoured, not malaligned, with the tip filling >half of the distal medullary canal
ETO: drill holes at least 12cm from GT tip, segment is 1/3 of femoral circumference, hinged anterolaterally on periosteum/muscle
Apply cables distal to the osteotomy before reaming; fix with cerclage wires or cables
Indications: well-fixed stem, difficult cement removal, varus remodelling of proximal femur, need for enhanced acetabular exposure
Q34What is the aim of assessment when a total hip replacement is loose?▸
Rule out infection
Assess symptoms
Q35What history and examination findings are relevant in a loose total hip replacement?▸
Pain and constitutional symptoms
Surgical details: timing of OT, initial post-op infection
Recent infection, wound condition and any sinus
Q36What investigations are required before revision hip surgery?▸
Obtain previous X-ray for comparison
Blood test for inflammatory markers
Hip aspiration on 2 different occasions for C/ST, cell count and alpha defensin
Pre-op CT for bone stock, column and rim integrity
CT angiogram for proximity of great vessels to the acetabular cup
Trace old records for implant size, brand and removal instruments
Q37What are the MSIS 2011 major criteria for periprosthetic joint infection?▸
Sinus tract communicating with the joint
+ve C/ST in 2 separate tissue/fluid samples
Q38What are the MSIS 2011 minor criteria for periprosthetic joint infection?▸
CRP/ESR
Synovial WBC count and synovial neutrophil %
1 C/ST +ve
5 neutrophils in HPF
Q39What are the chronic periprosthetic infection thresholds in the MSIS score?▸
ESR >30
CRP >10mg/L
Synovial fluid WBC >3000 cell/uL
PMN >80%
Q40What are the acute periprosthetic infection thresholds in the MSIS score?▸
ESR not reliable
CRP >100mg/L
Synovial fluid WBC >10,000 cell/uL
PMN >90%
Q41What initial post-op X-ray findings suggest the aseptic loosening is technique-related?▸
Poor cementation technique with <2mm cement mantle
Poor positioning: varus stem position or increased open angle of the cup
These cause abnormal stress onto the implant
Q42What surgical approach and instruments should be prepared for revision hip surgery?▸
Q47Describe the Paprosky classification of acetabular defects.▸
Type 1: minimal lysis
Type 2: <3cm superior migration, column intact, rim distorted, >50% contact surface; cementless if >2/3 rim fit, otherwise augment ring
Type 3: >3cm superior migration, column not intact
X-ray features assessed: superior migration, tear drop, ilioischial line, ischial lysis
Q48How is a contained acetabular defect managed in revision hip surgery?▸
Avoid the defect: high hip centre or medialise
Bone: autograft/allograft, structural or morselized, impaction bone grafting
Metal: metal wedge, jumbo (60mm)/oblong cup, revision ring (Muller/Ganz) if host contact <70%, anti-protrusio cage for discontinuity, mesh for uncontained defect
Cement
Q49How is an uncontained acetabular defect managed?▸
Convert to a contained defect using mesh
Then treat as contained, usually with bone graft + augment ring
Use cemented fixation as there is no bone ingrowth from bone graft
Q50Which revision stem is chosen for a contained femoral defect?▸
Cemented stem is poorly fixed due to poor interdigitation with lost cancellous bone and sclerosis
Prefer extensively coated long stem in good bone stock
Severe bone loss with a large canal cavity is difficult - needs an extra large implant with risk of fracture and stress shielding (extra large implant for initial stability --> easy fracture during OT, significant stress shielding)
Alternative: impaction bone grafting + cemented stem
Q51How are segmental or cortical femoral defects managed in revision hip surgery?▸
Small segmental/cortical defect: cortical onlay strut graft (onlay struft graft)
Impaction bone grafting + mesh
Gross proximal bone defect: tumour prosthesis
Q52Describe the technique of impaction bone grafting in the acetabulum.▸
Close acetabular segmental defects with flexible metal wire mesh
Fill the contained defect with a layer of morselized 8-10mm trabecular graft, impacted tightly with hammer and impactors
Cement the cup
Q53What is the role of cages in managing acetabular bone defects?▸
Reconstruct the defect with allograft or trabecular metal
Offload the graft by bridging the defect, anchoring to the ilium or ischium
Liner cemented into the cage
Q54What are the advantages of a jumbo cup?▸
Defined as >62mm in women and >66mm in men
Relatively simple
Increased host bone-cup contact area maximising ingrowth
Minimises migration by force dissipation over a large area
Decreases the need for bone graft
Q55What are the disadvantages of a jumbo cup?▸
Bone stock is not restored
Limited applicability in oblong defect - may ream away the posterior column or wall
High dislocation rate due to acetabular size:femoral head ratio (10%) - may use dual mobility
May raise the hip centre of rotation
Q56How is a Paprosky type IIA (cavitary) acetabular defect reconstructed?▸
Hemispherical cup
Q57How is a Paprosky type IIB (segmental defect <30% rim) acetabular defect reconstructed?▸
Hemispherical cup or jumbo cup
Q58How is a Paprosky type IIC (protrusion) acetabular defect reconstructed?▸
Medial cancellous allograft
Hemispherical cup
Impaction bone grafting
Q59How is a Paprosky type IIIA (spherical remodelling, up and out) acetabular defect reconstructed?▸
Large hemispherical cup
Q60How is a Paprosky type IIIB (oblong remodelling) acetabular defect reconstructed?▸
Structural autograft/allograft with hemispherical cup
Trabecular metal shell with superior augment
High hip centre with hemispherical cup
Q61How is a Paprosky IIIB acetabular defect without discontinuity managed?▸
Non-biological: cancellous allograft with cage
Structural allograft (posterior column with cage)
Biological: trabecular metal with augments
Triflange custom implant
Q62How is an acute pelvic discontinuity (Paprosky IIIB) managed?▸
Compression
Plate with cage and allograft
Internal plate with trabecular metal
Q63How is a chronic pelvic discontinuity (Paprosky IIIB) managed?▸
Distraction
Acetabular transplant
Trabecular metal with augments
Triflange implant
Q64Describe Paprosky femoral defect type I.▸
Minimal metaphyseal bone loss
Q65Describe Paprosky femoral defect type II.▸
Extension of metaphyseal bone loss with an intact diaphysis
Q66Describe Paprosky femoral defect type IIIA.▸
Extensive metadiaphyseal bone loss
At least 4cm of intact cortical bone in the diaphysis
Q67Describe Paprosky femoral defect type IIIB.▸
Extensive metadiaphyseal bone loss
less than 4cm intact cortical bone in the diaphysis
Q68Describe Paprosky femoral defect type IV.▸
Extensive metadiaphyseal bone loss
Non-supportive diaphysis
Q69What cementless stem options are available for femoral revision?▸