Acrylic antibiotic bead chains as an implant-based method of local infection prophylaxis and treatment
4 questions1 source pages1 fact-check flags
Images appear with the first
question taken from each source page — tap a question to open it.
4 questions
Q1What are antibiotic-containing acrylic beads made of?▸
PMMA cement loaded with gentamicin sulphate
Zirconium dioxide contrast medium, threaded on a metal wire
Q2What are the advantages of antibiotic beads?▸
High localised antibiotic concentration without systemic side effects
Reduce dead space
Q3What is the size and gentamicin content of each bead?▸
Each bead is 7mm in diameter
Contains 7.5g gentamicin per the speaker notes
Q4Why is gentamicin suitable for antibiotic beads?▸
Broad-spectrum aminoglycoside, effective against gram +ve and gram -ve bacteria
Bactericidal, heat stable and soluble
Low rate of resistance and allergy
Low MIC (minimal concentration in situ to inhibit bacterial growth)
Fact check
Each antibiotic bead is 7mm and contains 7.5g gentamicin — Unit error: grams should be milligrams — Septopal PMMA beads are 7mm diameter and contain gentamicin in milligram amounts (reported around 4.5-7.5 mg per bead), not 7.5 g — source